When Moon is in 8th house there will be prosperity if the person is religious in nature. Serving elders will bless him with a long life.
If Venus is malefic, Saturn too becomes malefic and indicates loss of wealth, death by weapon, in-laws and offspring getting destroyed.
When Mercury and Saturn are malefic it indicates mothers death at 4, 8, 24.
Eighth House in Horoscope
This house indicates the death and longevity of the individual. It also represents his material prosperity, mental wellbeing of the native.
The angry nature, chronic disease, longevity and death are indicated by this house. Read more about the Eighth House.